Structure of PDB 2fp7 Chain A Binding Site BS01

Receptor Information
>2fp7 Chain A (length=40) Species: 11082 (West Nile virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETDMWIERTADITWESDAEITGSSERVDVRLDDDGNFQLM
Ligand information
Receptor-Ligand Complex Structure
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PDB2fp7 Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.
Resolution1.68 Å
Binding residue
(original residue number in PDB)		G83 F85 Q86
Binding residue
(residue number reindexed from 1)		G35 F37 Q38
Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Cellular Component
GO:0044423 virion component

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Molecular Function
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Cellular Component
External links
PDB RCSB:2fp7, PDBe:2fp7, PDBj:2fp7
PDBsum2fp7
PubMed16532006
UniProtP06935|POLG_WNV Genome polyprotein

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