Structure of PDB 2foj Chain A Binding Site BS01
Receptor Information
>2foj Chain A (length=137) Species:
9606
(Homo sapiens) [
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TSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFQKSVGFF
LQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFS
NFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAW
Ligand information
>2foj Chain B (length=7) Species:
9606
(Homo sapiens) [
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GARAHSS
Receptor-Ligand Complex Structure
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PDB
2foj
Molecular recognition of p53 and MDM2 by USP7/HAUSP
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
M100 F118 R152 D164 W165 G166 F167 S168
Binding residue
(residue number reindexed from 1)
M38 F50 R84 D96 W97 G98 F99 S100
Enzymatic activity
Enzyme Commision number
3.4.19.12
: ubiquitinyl hydrolase 1.
External links
PDB
RCSB:2foj
,
PDBe:2foj
,
PDBj:2foj
PDBsum
2foj
PubMed
16474402
UniProt
Q93009
|UBP7_HUMAN Ubiquitin carboxyl-terminal hydrolase 7 (Gene Name=USP7)
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