Structure of PDB 2fn8 Chain A Binding Site BS01

Receptor Information
>2fn8 Chain A (length=292) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGKMAIVISTLNNPWFVVLAETAKQRAEQLGYEATIFDSQNDTAKESAHF
DAIIAAGYDAIIFNPTDADGSIANVKRAKEAGIPVFCVDRGINARGLAVA
QIYSDNYYGGVLMGEYFVKFLKEKYPDAKEIPYAELLGILSAQPTWDRSN
GFHSVVDQYPEFKMVAQQSAEFDRDTAYKVTEQILQAHPEIKAIWCGNDA
MALGAMKACEAAGRTDIYIFGFDGAEDVINAIKEGKQIVATIMQFPKLMA
RLAVEWADQYLRGERSFPEIVPVTVELVTRENIDKYTAYGRK
Ligand information
Ligand IDRIP
InChIInChI=1S/C5H10O5/c6-2-1-10-5(9)4(8)3(2)7/h2-9H,1H2/t2-,3-,4-,5-/m1/s1
InChIKeySRBFZHDQGSBBOR-TXICZTDVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C1C(C(C(C(O1)O)O)O)O
OpenEye OEToolkits 1.5.0C1[C@H]([C@H]([C@H]([C@@H](O1)O)O)O)O
CACTVS 3.341O[CH]1CO[CH](O)[CH](O)[CH]1O
CACTVS 3.341O[C@@H]1CO[C@@H](O)[C@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)COC(O)C1O
FormulaC5 H10 O5
Namebeta-D-ribopyranose;
beta-D-ribose;
D-ribose;
ribose;
RIBOSE(PYRANOSE FORM)
ChEMBLCHEMBL1159662
DrugBankDB04286
ZINCZINC000004097544
PDB chain2fn8 Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fn8 Ligand-induced conformational changes in a thermophilic ribose-binding protein.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		N13 W15 F16 D89 R90 R148 F172 N198 D223 Q244
Binding residue
(residue number reindexed from 1)		N13 W15 F16 D89 R90 R148 F172 N198 D223 Q244
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:2fn8, PDBe:2fn8, PDBj:2fn8
PDBsum2fn8
PubMed19019243
UniProtQ9X053

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