Structure of PDB 2flc Chain A Binding Site BS01

Receptor Information
>2flc Chain A (length=247) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLVELGSKTAKDGFKNEKDIADRFENWKENSEAQDWLVTMGHNLDEIKS
VKAVVLSGYKSDINVQVLVFYKDALDIHNIQVKLVSNKRGFNQIDKHWLA
HYQEMWKFDDNLLRILRHFTGELPPYHSNTKDKRRMFMTEFSQEEQNIVL
NWLEKNRVLVLTDILRGRGDFAAEWVLVAQKVSNNARWILRNINEVLQHY
GSGDISLSPRGSINFGRVTIQRKGGDNGRETANMLQFKIDPTELFDI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2flc DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Resolution2.59 Å
Binding residue
(original residue number in PDB)
G58 Y59 Q93 K96 H97
Binding residue
(residue number reindexed from 1)
G58 Y59 Q93 K96 H97
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2flc, PDBe:2flc, PDBj:2flc
PDBsum2flc
PubMed16473850
UniProtQ5I6E6

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