Structure of PDB 2fib Chain A Binding Site BS01
Receptor Information
>2fib Chain A (length=250) Species:
9606
(Homo sapiens) [
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VQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWT
VFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAI
PYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDG
FDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAG
HLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
Ligand information
>2fib Chain B (length=4) [
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GPRP
Receptor-Ligand Complex Structure
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PDB
2fib
The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
Resolution
2.01 Å
Binding residue
(original residue number in PDB)
F295 D297 D301 T305 F322 Q329 K338 C339 H340 D364
Binding residue
(residue number reindexed from 1)
F153 D155 D159 T163 F180 Q187 K196 C197 H198 D222
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0007596
blood coagulation
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Biological Process
External links
PDB
RCSB:2fib
,
PDBe:2fib
,
PDBj:2fib
PDBsum
2fib
PubMed
9207064
UniProt
P02679
|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)
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