Structure of PDB 2fge Chain A Binding Site BS01

Receptor Information
>2fge Chain A (length=979) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEAEKLGFEKVSEEFISECKSKAILFKHKKTGCEVMSVSNEDENKVFGVV
FRTPPKDSTGIPHILQHSVLCGSRKYPVKEPFVELLKGSLHTFLNAFTYP
DRTCYPVASTNTKDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWHYELNDP
SEDISYKGVVFNEMKGVYSQPDNILGRIAQQALSPENTYGVDSGGDPKDI
PNLTFEEFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDMFEASPS
PNSSKIKFQKLFSEPVRLVEKYPAGRDGDLKKKHMLCVNWLLSEKPLDLQ
TQLALGFLDHLMLGTPASPLRKILLESGLGEALVSSGLSDELLQPQFGIG
LKGVSEENVQKVEELIMDTLKKLAEEGFDNDAVEASMNTIEFSLRENNTG
SFPRGLSLMLQSISKWIYDMDPFEPLKYTEPLKALKTRIAEEGSKAVFSP
LIEKLILNNSHRVTIEMQPDPEKATQEEVEEKNILEKVKAAMTEEDLAEL
ARATEELKLKQETPDPPEALRCVPSLNLGDIPKEPTYVPTEVGDINGVKV
LRHDLFTNDIIYTEVVFDIGSLKHELLPLVPLFCQSLLEMGTKDLTFVQL
NQLIGRKTGGISVYPLTSSVRGKDEPCSKIIVRGKSMAGRADDLFNLMNC
LLQEVQFTDQQRFKQFVSQSRARMENRLRGSGHGIAAARMDAMLNIAGWM
SEQMGGLSYLEFLHTLEKKVDEDWEGISSSLEEIRRSLLARNGCIVNMTA
DGKSLTNVEKSVAKFLDLLPENPSGGLVTWDGRLPLRNEAIVIPTQVNYV
GKAGNIYSTGYELDGSAYVISKHISNTWLWDRVRVSGGAYGGFCDFDSHS
GVFSYLSYRDPNLLKTLDIYDGTGDFLRGLDVDQETLTKAIIGTIGDVDS
YQLPDAKGYSSLLRHLLGVTDEERQRKREEILTTSLKDFKDFAQAIDVVR
DKGVAVAVASAEDIDAANNERSNFFEVKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fge The closed structure of presequence protease PreP forms a unique 10 000 A(3) chamber for proteolysis
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Q80 H81 E94 F96 N109 A110 F111 T112 Y113 Y854
Binding residue
(residue number reindexed from 1)		Q66 H67 E80 F82 N95 A96 F97 T98 Y99 Y840
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0016485 protein processing
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009570 chloroplast stroma
GO:0009941 chloroplast envelope
GO:0048046 apoplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fge, PDBe:2fge, PDBj:2fge
PDBsum2fge
PubMed16601675
UniProtQ9LJL3|PREP1_ARATH Presequence protease 1, chloroplastic/mitochondrial (Gene Name=PREP1)

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