Structure of PDB 2fg5 Chain A Binding Site BS01

Receptor Information
>2fg5 Chain A (length=165) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNE
LHKFLIWDTAGQERFHSLAPMYYRGSAAAVIVYDITKQDSFYTLKKWVKE
LKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEYAESIGAIVVETSAKNA
INIEELFQGISRQIP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2fg5 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2fg5 Crystal structure of human RAB31 in complex with a GTP analogue
Resolution2.801 Å
Binding residue
(original residue number in PDB)		S19 T37
Binding residue
(residue number reindexed from 1)		S17 T35
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) V22
Catalytic site (residue number reindexed from 1) V20
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2fg5, PDBe:2fg5, PDBj:2fg5
PDBsum2fg5
PubMed
UniProtQ13636|RAB31_HUMAN Ras-related protein Rab-31 (Gene Name=RAB31)

[Back to BioLiP]