Structure of PDB 2ffw Chain A Binding Site BS01

Receptor Information
>2ffw Chain A (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVT
CEVSYCDECLKATHPNKKPFTGHRLIEP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2ffw Chain A Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ffw Solution Structure of the RBCC/TRIM B-box1 Domain of Human MID1: B-box with a RING.
ResolutionN/A
Binding residue
(original residue number in PDB)		C119 C122 C142 C145
Binding residue
(residue number reindexed from 1)		C33 C36 C56 C59
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2ffw, PDBe:2ffw, PDBj:2ffw
PDBsum2ffw
PubMed16529770
UniProtO15344|TRI18_HUMAN E3 ubiquitin-protein ligase Midline-1 (Gene Name=MID1)

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