Structure of PDB 2fe3 Chain A Binding Site BS01

Receptor Information
>2fe3 Chain A (length=141) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPN
MSVATVYNNLRVFRESGLVKELTYGDASSRFDFVTSDHYHAICENCGKIV
DFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKEN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2fe3 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2fe3 Crystal structure of the apo-PerR-Zn protein from Bacillus subtilis.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		C96 C99 C136 C139
Binding residue
(residue number reindexed from 1)		C93 C96 C133 C136
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001216 DNA-binding transcription activator activity
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
GO:1900376 regulation of secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0032993 protein-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fe3, PDBe:2fe3, PDBj:2fe3
PDBsum2fe3
PubMed16925555
UniProtP71086|PERR_BACSU Peroxide operon regulator (Gene Name=perR)

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