Structure of PDB 2fdm Chain A Binding Site BS01

Receptor Information
>2fdm Chain A (length=361) Species: 9940 (Ovis aries) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEW
NDVTLYDTLNTLKNRNPKLKTLLSVGGWNFGPERFSAIASKTQSRRTFIK
SVPPFLRTHGFDGLDLAWLYPGRRDKRHLTTLVKEMKAEFIREAQAGTEQ
LLLSAAVSAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSP
LFAGNEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSFTLASSKT
DVGAPVSGPGVPGRFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKG
NQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPL
TSAVKDVLAEV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fdm Crystal structure of the ternary complex of signalling glycoprotein frm sheep (SPS-40) with hexasaccharide (NAG6) and peptide Trp-Pro-Trp at 3.0A resolution
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A190 W191
Binding residue
(residue number reindexed from 1)		A190 W191
Enzymatic activity
Catalytic site (original residue number in PDB) D115 A117 L119 Y185
Catalytic site (residue number reindexed from 1) D115 A117 L119 Y185
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008061 chitin binding
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0009612 response to mechanical stimulus
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0030324 lung development
GO:0032757 positive regulation of interleukin-8 production
GO:0034612 response to tumor necrosis factor
GO:0045766 positive regulation of angiogenesis
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0070741 response to interleukin-6
GO:0071356 cellular response to tumor necrosis factor
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0048471 perinuclear region of cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fdm, PDBe:2fdm, PDBj:2fdm
PDBsum2fdm
PubMed
UniProtQ6TMG6|CH3L1_SHEEP Chitinase-3-like protein 1 (Gene Name=CHI3L1)

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