Structure of PDB 2fci Chain A Binding Site BS01
Receptor Information
>2fci Chain A (length=105) Species:
9913
(Bos taurus) [
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GSPGIHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFR
AEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPIN
EENSS
Ligand information
>2fci Chain B (length=13) Species:
9913
(Bos taurus) [
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DTEVYESPYADPE
Receptor-Ligand Complex Structure
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PDB
2fci
Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase
Resolution
N/A
Binding residue
(original residue number in PDB)
R18 A19 R37 R39 N40 F49 K54 I55 K56 C58 R59 L69 G70 N71 Y84 Y90
Binding residue
(residue number reindexed from 1)
R18 A19 R37 R39 N40 F49 K54 I55 K56 C58 R59 L69 G70 N71 Y84 Y90
Enzymatic activity
Enzyme Commision number
3.1.4.11
: phosphoinositide phospholipase C.
External links
PDB
RCSB:2fci
,
PDBe:2fci
,
PDBj:2fci
PDBsum
2fci
PubMed
16410013
UniProt
P08487
|PLCG1_BOVIN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (Gene Name=PLCG1)
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