Structure of PDB 2f8k Chain A Binding Site BS01
Receptor Information
>2f8k Chain A (length=84) Species:
4932
(Saccharomyces cerevisiae) [
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SSMNPKSLTDPKLLKNIPMWLKSLRLHKYSDALSGTPWIELIYLDDETLE
KKGVLALGARRKLLKAFGIVIDYKERDLIDRSAY
Ligand information
>2f8k Chain B (length=16) [
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uaaucuuugacagauu
.<<<<<.....>>>>>
Receptor-Ligand Complex Structure
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PDB
2f8k
Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
K461 R464 L465 H466 K467 A495 L496 G497 R500
Binding residue
(residue number reindexed from 1)
K22 R25 L26 H27 K28 A56 L57 G58 R61
Binding affinity
PDBbind-CN
: Kd=25nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003729
mRNA binding
Biological Process
GO:0043488
regulation of mRNA stability
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Molecular Function
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Biological Process
External links
PDB
RCSB:2f8k
,
PDBe:2f8k
,
PDBj:2f8k
PDBsum
2f8k
PubMed
16429151
UniProt
Q08831
|VTS1_YEAST RNA-binding protein VTS1 (Gene Name=VTS1)
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