Structure of PDB 2f74 Chain A Binding Site BS01

Receptor Information
>2f74 Chain A (length=275) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPW
MEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGC
DLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSG
AAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTL
RCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPL
GKEQNYTCRVYHEGLPEPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2f74 Structural Basis of the Differential Stability and Receptor Specificity of H-2D(b) in Complex with Murine versus Human beta(2)-Microglobulin.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
Y7 R62 E63 K66 Q70 W73 S77 N80 Y84 Q97 S99 Y123 T143 K146 W147 H155 Y156 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 R61 E62 K65 Q69 W72 S76 N79 Y83 Q96 S98 Y122 T142 K145 W146 H154 Y155 Y158 E162 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2f74, PDBe:2f74, PDBj:2f74
PDBsum2f74
PubMed16375919
UniProtP01899|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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