Structure of PDB 2f59 Chain A Binding Site BS01

Receptor Information

>2f59 Chain A (length=146) Species: 235 (Brucella abortus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

APHLLIVEARFYDDLADALLDGAKAALDEAGATYDVVTVPGALEIPATIS
FALDGADNGGTEYDGFVALGTVIRGETYHFDIVSNESCRALTDLSVEESI
AIGNGILTVENEEQAWVHARREDKDKGGFAARAALTMIGLRKKFGA

Ligand information

InChI=1S/Ca/q+2

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Ca

Name

CALCIUM ION

PDB chain

2f59 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	2f59 Structural and Kinetic Properties of Lumazine Synthase Isoenzymes in the Order Rhizobiales
Resolution	2.3 Å
Binding residue (original residue number in PDB)	A67 E73
Binding residue (residue number reindexed from 1)	A56 E62
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H90
Catalytic site (residue number reindexed from 1)	H79
Enzyme Commision number	2.5.1.78: 6,7-dimethyl-8-ribityllumazine synthase.

Gene Ontology

	Molecular Function
GO:0000906	6,7-dimethyl-8-ribityllumazine synthase activity
GO:0016740	transferase activity

	Biological Process
GO:0009231	riboflavin biosynthetic process

	Cellular Component
GO:0005829	cytosol
GO:0009349	riboflavin synthase complex

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Cellular Component

External links

PDB	RCSB:2f59, PDBe:2f59, PDBj:2f59
PDBsum	2f59
PubMed	17854827
UniProt	Q57DY1\|RISB1_BRUAB 6,7-dimethyl-8-ribityllumazine synthase 1 (Gene Name=ribH1)

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