Structure of PDB 2f4m Chain A Binding Site BS01

Receptor Information
>2f4m Chain A (length=295) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDSTILKVLQSNIQHVQLYENPVLQEKALTCIPVSELKRKAQEKLFRARK
LDKGTNVSDEDFLLLELLHWFKEEFFRWVNNIVCSKCGGETRSRDEALLP
NDDELKWGAKNVENHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCF
TLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYE
IGWGKKLSYIIAFSKDEVVDVTWRYSCKHDEVMSRRTKVKEELLRETING
LNKQRQLSLSESRRKELLQRIIVELVEFISPKTPRPGLEHHHHHH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2f4m Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2f4m Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		C247 C250 C280 C283
Binding residue
(residue number reindexed from 1)		C84 C87 C117 C120
Annotation score4
Enzymatic activity
Enzyme Commision number 3.5.1.52: peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase.
External links
PDB RCSB:2f4m, PDBe:2f4m, PDBj:2f4m
PDBsum2f4m
PubMed16500903
UniProtQ9JI78|NGLY1_MOUSE Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (Gene Name=Ngly1)

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