Structure of PDB 2f4g Chain A Binding Site BS01

Receptor Information
>2f4g Chain A (length=129) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Ligand information
Ligand IDBRJ
InChIInChI=1S/C2H5BrO/c3-1-2-4/h4H,1-2H2
InChIKeyLDLCZOVUSADOIV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04BrCCO
CACTVS 3.341OCCBr
OpenEye OEToolkits 1.5.0C(CBr)O
FormulaC2 H5 Br O
Name2-BROMOETHANOL
ChEMBLCHEMBL468583
DrugBank
ZINCZINC000004978447
PDB chain2f4g Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2f4g On the edge of the denaturation process: Application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations.
Resolution1.654 Å
Binding residue
(original residue number in PDB)		Q57 W63 A107 W108
Binding residue
(residue number reindexed from 1)		Q57 W63 A107 W108
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E35 N46 D48 S50 D52 N59
Catalytic site (residue number reindexed from 1) E35 N46 D48 S50 D52 N59
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0005515 protein binding
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
Biological Process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2f4g, PDBe:2f4g, PDBj:2f4g
PDBsum2f4g
PubMed16600702
UniProtP00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)

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