Structure of PDB 2f3o Chain A Binding Site BS01

Receptor Information
>2f3o Chain A (length=773) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRIEKLIKKVSKPARLSVERCRLYTESMKQTEGEPMIIRQAKALKHVLEN
IPIQILDSELIVGTMLPNPPGAIIFPEGVGLRIINELDSLPNRETNRLMV
DEEDAKVLREEIAPYWQRKTIEAFAFPLMPDIMQILYTGSVFVLTEIAGI
SHVAVNYPYLLRRGFRWFLEESERRIRALEESGVYEGEKYSFYQAAKIVS
EAVINYGLRYSKLAEELAESEDGERREELLKIAEICRKVPAEKPETFWEA
VQFVWLVQSALHQENYEQAISMGRIDQYLYPFFKKDIGEGRINRELAFDI
LANLWIKTNEIVPAFDSLLEQYFSGQATNQAVTIGGCDIYGNDATNELTY
LMLEVTDRLRLRQPNVHVRINKGSPESFLKRLAEAISSGCNNLALFFDDA
AVKALKNAEVDDRDALNYTTDGCVEIAPFGNSFTSSDAALINVAKALEYA
LNEGVDLQFGYEFGAKTEKPKFLEDLLEKLREQVSHIVKLVVRGSNVLSY
ANAEVKPTPLLSLCVEDCFEKGVDVSRGGARYNFTGIQAVGIADVGDSLV
AIEGALNAGYSMDDIVEACRKNFVGYEKLHKLLLQSPKYGNDDDAADKYT
KMVLEWYCEEVNRHRNFRGGKFAAGCYPMTTNVGFGFFTSALPSGRKSGE
PLNPGVSPSTGMDREGVTAVINSASKLSYENLPNGASLTINLSSDVLGEK
GDAVIEALIKSSMELGVMHVQFNILKEDLLRKAQQEPEKYRWLLVRVAGW
SAYFVELSRPVQEEVIRRISCRI
Ligand information
Ligand IDGOL
InChIInChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(CO)O)O
ACDLabs 12.01
CACTVS 3.370		OCC(O)CO
FormulaC3 H8 O3
NameGLYCEROL;
GLYCERIN;
PROPANE-1,2,3-TRIOL
ChEMBLCHEMBL692
DrugBankDB09462
ZINCZINC000000895048
PDB chain2f3o Chain A Residue 778 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2f3o Crystal structure of a glycyl radical enzyme from Archaeoglobus fulgidus
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H155 Q271 N332 C426 E428 D440 M632
Binding residue
(residue number reindexed from 1)		H152 Q268 N329 C423 E425 D437 M629
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) N332 G425 C426 G752
Catalytic site (residue number reindexed from 1) N329 G422 C423 G749
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:2f3o, PDBe:2f3o, PDBj:2f3o
PDBsum2f3o
PubMed16414072
UniProtO28823

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