Structure of PDB 2f30 Chain A Binding Site BS01

Receptor Information
>2f30 Chain A (length=129) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Ligand information
Ligand IDURE
InChIInChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChIKeyXSQUKJJJFZCRTK-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)(N)N
CACTVS 3.341NC(N)=O
ACDLabs 10.04O=C(N)N
FormulaC H4 N2 O
NameUREA
ChEMBLCHEMBL985
DrugBankDB03904
ZINCZINC000008214514
PDB chain2f30 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2f30 On the edge of the denaturation process: Application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		N59 A107 W108
Binding residue
(residue number reindexed from 1)		N59 A107 W108
Annotation score3
Enzymatic activity
Catalytic site (original residue number in PDB) E35 N46 D48 S50 D52 N59
Catalytic site (residue number reindexed from 1) E35 N46 D48 S50 D52 N59
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0005515 protein binding
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
Biological Process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2f30, PDBe:2f30, PDBj:2f30
PDBsum2f30
PubMed16600702
UniProtP00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)

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