Structure of PDB 2ezv Chain A Binding Site BS01
Receptor Information
>2ezv Chain A (length=267) Species:
68197
(Streptomyces fimbriatus) [
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MHQDYRELSLDELESVEKQTLRTIVQALQQYSKEAKSIFETTAADSSGEV
IVLAEDITQYALEVAETYPINRRFAGFIDYKRVRWLPSPHGLLPQVLLVD
AKASTEKNRDTLQRSQLPMDAEFRNTSSGEVVTMEAGVIPHLMLQSANDG
VLPAVTTSIFVHFYYRELKEGRYRELKSIYVLSLPHARLKQRYNPDPDTS
FFGAGKHSPARGEVARIRVYFDRLKEACPWRLQELHYSADSEYTQPRWRD
LNDAGHEVTKEFLFLER
Ligand information
>2ezv Chain F (length=15) [
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tggccaacaaggcct
Receptor-Ligand Complex Structure
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PDB
2ezv
A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
S46 R109 T126 S127 A206 G207 K208 S210 P211 A212 R213 E215 R220 Y222
Binding residue
(residue number reindexed from 1)
S46 R109 T126 S127 A204 G205 K206 S208 P209 A210 R211 E213 R218 Y220
Enzymatic activity
Enzyme Commision number
3.1.21.4
: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519
endonuclease activity
GO:0009036
type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307
DNA restriction-modification system
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Molecular Function
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Biological Process
External links
PDB
RCSB:2ezv
,
PDBe:2ezv
,
PDBj:2ezv
PDBsum
2ezv
PubMed
16308566
UniProt
O52512
|T2S1_STRFI Type II restriction enzyme SfiI (Gene Name=sfiIR)
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