Structure of PDB 2evu Chain A Binding Site BS01

Receptor Information
>2evu Chain A (length=245) Species: 79929 (Methanothermobacter marburgensis str. Marburg) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVSLTKRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLG
GLGDWVAIGLAFGFAIAASIYALGNISGCHINPAVTIGLWSVKKFPGREV
VPYIIAQLLGAAFGSFIFLQCAGIGAATVGGLGATAPFPGISYWQAMLAE
VVGTFLLMITIMGIAVDERAPKGFAGIIIGLTVAGIITTLGNISGSSLNP
ARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALTYQYLTS
Ligand information
Ligand IDGOL
InChIInChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(CO)O)O
ACDLabs 12.01
CACTVS 3.370		OCC(O)CO
FormulaC3 H8 O3
NameGLYCEROL;
GLYCERIN;
PROPANE-1,2,3-TRIOL
ChEMBLCHEMBL692
DrugBankDB09462
ZINCZINC000000895048
PDB chain2evu Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2evu Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		I66 I81 N82
Binding residue
(residue number reindexed from 1)		I66 I81 N82
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015250 water channel activity
GO:0015267 channel activity
Biological Process
GO:0006833 water transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2evu, PDBe:2evu, PDBj:2evu
PDBsum2evu
PubMed16361443
UniProtQ9C4Z5|AQPM_METTM Aquaporin AqpM (Gene Name=aqpM)

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