Structure of PDB 2etz Chain A Binding Site BS01
Receptor Information
>2etz Chain A (length=108) Species:
10090
(Mus musculus) [
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NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKA
IISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVT
RLRYPVCG
Ligand information
>2etz Chain B (length=6) Species:
10090
(Mus musculus) [
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ADYEPP
Receptor-Ligand Complex Structure
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PDB
2etz
Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide.
Resolution
N/A
Binding residue
(original residue number in PDB)
S17 R18 S39 T46 K62 K67 V78 A79
Binding residue
(residue number reindexed from 1)
S14 R15 S36 T43 K59 K64 V75 A76
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:2etz
,
PDBe:2etz
,
PDBj:2etz
PDBsum
2etz
PubMed
16436281
UniProt
Q03526
|ITK_MOUSE Tyrosine-protein kinase ITK/TSK (Gene Name=Itk)
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