Structure of PDB 2ere Chain A Binding Site BS01

Receptor Information

>2ere Chain A (length=60) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

FACVECRQQKSKCDAHPCTKCAKKNVPCILKRDFRRTYKRARNEAIEKRF
KELTRTLTNL

Ligand information

>2ere Chain C (length=15) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ttgccggtaccggca

Receptor-Ligand Complex Structure

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PDB	2ere Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	A36 R41 K44 K46 R79
Binding residue (residue number reindexed from 1)	A2 R7 K10 K12 R40
Binding affinity	PDBbind-CN: Kd=30nM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0008270	zinc ion binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:2ere, PDBe:2ere, PDBj:2ere
PDBsum	2ere
PubMed	16615914
UniProt	P08638\|LEUR_YEAST Regulatory protein LEU3 (Gene Name=LEU3)

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