Structure of PDB 2epf Chain A Binding Site BS01

Receptor Information

>2epf Chain A (length=207) Species: 8671 (Pseudechis porphyriacus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NYQKEIVDKHNALRRSVKPTARNMLQMKWNSHAAQNAKRWADRCTFAHSP
PNTRTVGKLRCGENIFMSSQPFPWSGVVQAWYDEIKNFVYGIGAKPPGSV
IGHYTQVVWYKSHLIGCASAKCSSSKYLYVCQYCPAGNIRGSIATPYKSG
PPCADCPSACVNRLCTNPCNYNNDFSNCKSLAKKSKCQTEWIKKKCPASC
FCHNKII

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

2epf Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2epf Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domain
Resolution	2.3 Å
Binding residue (original residue number in PDB)	H51 H106
Binding residue (residue number reindexed from 1)	H48 H103
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0046872	metal ion binding
GO:0090729	toxin activity
GO:0099106	ion channel regulator activity

	Biological Process
GO:0035821	modulation of process of another organism

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space

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Molecular Function

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Cellular Component

External links

PDB	RCSB:2epf, PDBe:2epf, PDBj:2epf
PDBsum	2epf
PubMed	18931410
UniProt	Q8AVA3\|CRVP_PSEPO Cysteine-rich venom protein pseudecin

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