Structure of PDB 2enx Chain A Binding Site BS01

Receptor Information

>2enx Chain A (length=310) Species: 205921 (Streptococcus agalactiae A909) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SKILVFGHQNPDSDAIGSSVAFAYLAKEAWGLDTEAVALGTPNEETAYVL
DYFGVQAPRVVESAKAEGVETVILTDHNEFQQSISDIKDVTVYGVVDHHR
VANFETANPLYMRLEPVGSASSIVYRMFKENGVSVPKELAGLLLSGLISD
TLLLKSPTTHASDIPVAKELAELAGVNLEEYGLEMLKAGTNLSSKTAAEL
IDIDAKTFELNGEAVRVAQVNTVDINDILARQEEIEVAIQEAIVTEGYSD
FVLMITDIVNSNSEILALGSNMAKVEAAFEFTLENNHAFLAGAVSRKKQV
VPQLTESYNA

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

2enx Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2enx Structure of the Streptococcus agalactiae family II inorganic pyrophosphatase at 2.80 A resolution
Resolution	2.8 Å
Binding residue (original residue number in PDB)	H9 D13 A16 D77
Binding residue (residue number reindexed from 1)	H8 D12 A15 D76
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.6.1.1: inorganic diphosphatase.

Gene Ontology

	Molecular Function
GO:0004427	inorganic diphosphate phosphatase activity
GO:0016462	pyrophosphatase activity
GO:0016787	hydrolase activity
GO:0030145	manganese ion binding
GO:0046872	metal ion binding

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:2enx, PDBe:2enx, PDBj:2enx
PDBsum	2enx
PubMed	17505113
UniProt	Q3K0B5\|PPAC_STRA1 Probable manganese-dependent inorganic pyrophosphatase (Gene Name=ppaC)

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