Structure of PDB 2ea6 Chain A Binding Site BS01

Receptor Information
>2ea6 Chain A (length=69) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSSGSSGTGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLR
DSLKNANTCPTCRKKINHK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2ea6 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ea6 Solution Structure of the RING domain of the human ring finger protein 4
ResolutionN/A
Binding residue
(original residue number in PDB)		C18 C21 C45 C48
Binding residue
(residue number reindexed from 1)		C18 C21 C45 C48
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2ea6, PDBe:2ea6, PDBj:2ea6
PDBsum2ea6
PubMed
UniProtP78317|RNF4_HUMAN E3 ubiquitin-protein ligase RNF4 (Gene Name=RNF4)

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