Structure of PDB 2e9s Chain A Binding Site BS01

Receptor Information
>2e9s Chain A (length=164) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTV
RLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVR
TERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYN
VKQLFRRVASALLE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2e9s Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2e9s The structure of human neuronal Rab6B in the active and inactive form
Resolution1.78 Å
Binding residue
(original residue number in PDB)		T27 T45
Binding residue
(residue number reindexed from 1)		T15 T33
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q72
Catalytic site (residue number reindexed from 1) Q60
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2e9s, PDBe:2e9s, PDBj:2e9s
PDBsum2e9s
PubMed
UniProtQ9NRW1|RAB6B_HUMAN Ras-related protein Rab-6B (Gene Name=RAB6B)

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