Structure of PDB 2e7i Chain A Binding Site BS01

Receptor Information
>2e7i Chain A (length=344) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFINIDPLQTGGKLTEEARQALLEWPPIHDFIHNQLPKFLGCDVARVTNG
AREAKFAVMHSLAKKDAWVVMDENCHYSSYVAAERAGLNIALVPKTDYPD
YAITPENFAQTIEETKKRGEVVLALITYPDGNYGNLPDVKKIAKVCSEYD
VPLLVNGAYAIGRMPVSLKEIGADFIVGSGHKSMAASGPIGVMGMKEEWA
EIVLRRSEKYKNKEVELLGCTARGATIITLMASFPHVRERIKRWDEEVEK
ARRFAAEMEKLGIKQLGDNPHNHDLMFFHAEVLYEISKKAKGGRFFLYRE
LKSRKIHGIKPGLTRYFKLSTYGLSDEEVDYVLNAFKEIIEKYS
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain2e7i Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2e7i Structural Insights into the Second Step of RNA-dependent Cysteine Biosynthesis in Archaea: Crystal Structure of Sep-tRNA:Cys-tRNA Synthase from Archaeoglobus fulgidus
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R267 R270
Binding residue
(residue number reindexed from 1)		R240 R243
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.73: O-phospho-L-seryl-tRNA:Cys-tRNA synthase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0043766 Sep-tRNA:Cys-tRNA synthase activity
Biological Process
GO:0006412 translation
GO:0071952 conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA

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Molecular Function
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Biological Process
External links
PDB RCSB:2e7i, PDBe:2e7i, PDBj:2e7i
PDBsum2e7i
PubMed17512006
UniProtO30207|SPSS1_ARCFU O-phospho-L-seryl-tRNA:Cys-tRNA synthase 1 (Gene Name=AF_0028)

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