Structure of PDB 2e6w Chain A Binding Site BS01

Receptor Information
>2e6w Chain A (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDA
PAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2e6w Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2e6w Solution structure and calcium-binding properties of EF-hands 3 and 4 of calsenilin.
ResolutionN/A
Binding residue
(original residue number in PDB)		D175 N177 D179 Y181 E186
Binding residue
(residue number reindexed from 1)		D15 N17 D19 Y21 E26
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2e6w, PDBe:2e6w, PDBj:2e6w
PDBsum2e6w
PubMed17962406
UniProtQ9Y2W7|CSEN_HUMAN Calsenilin (Gene Name=KCNIP3)

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