Structure of PDB 2dyh Chain A Binding Site BS01
Receptor Information
>2dyh Chain A (length=296) Species:
10090
(Mus musculus) [
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VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGL
LYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDG
HIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLY
AVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAG
GYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYD
GHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQ
Ligand information
>2dyh Chain B (length=6) Species:
10090
(Mus musculus) [
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WRQDID
Receptor-Ligand Complex Structure
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PDB
2dyh
Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
Y334 N382 R415 S508 G509 Y525 S555 A556 Y572 F577 S602
Binding residue
(residue number reindexed from 1)
Y11 N59 R92 S185 G186 Y202 S232 A233 Y249 F254 S279
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2dyh
,
PDBe:2dyh
,
PDBj:2dyh
PDBsum
2dyh
PubMed
17785452
UniProt
Q9Z2X8
|KEAP1_MOUSE Kelch-like ECH-associated protein 1 (Gene Name=Keap1)
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