Structure of PDB 2dvq Chain A Binding Site BS01

Receptor Information
>2dvq Chain A (length=114) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMD
MGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKI
FLQKVASMPQEEQE
Ligand information
>2dvq Chain P (length=8) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KGLGKGGA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2dvq Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain.
Resolution2.04 Å
Binding residue
(original residue number in PDB)
D112 I116 Y155 N156 D160 I162
Binding residue
(residue number reindexed from 1)
D40 I44 Y83 N84 D88 I90
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2dvq, PDBe:2dvq, PDBj:2dvq
PDBsum2dvq
PubMed20048151
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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