Structure of PDB 2du6 Chain A Binding Site BS01

Receptor Information
>2du6 Chain A (length=534) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFDPQKYRELAEKDFEAAWKAGKEILAERSPNELYPRVGFSFGKEHPLF
ATIQRLREAYLSIGFSEVVNPLIVEDVHVKKQFGREALAVLDRCFYLATL
PKPNVGISAEKIRQIEAITKREVDSKPLQEIFHRYKKGEIDGDDLSYLIA
EVLDVDDITAVKILDEVFPEFKELKPISSTLTLRSHMTTGWFITLSHIAD
KLPLPIKLFSIDRCFRREQGEDATRLYTYFSASCVLVDEELSVDDGKAVA
EALLRQFGFENFRFRKDEKRSKYYIPDTQTEVFAFHPKLVGSSTKYSDGW
IEIATFGIYSPTALAEYDIPYPVMNLGLGVERLAMILYGYDDVRKMVYPQ
IHGEIKLSDLDIAREIKVKEVPQTAVGLKIAQSIVETAEKHASEPSPCSF
LAFEGEMMGRNVRVYVVNENENTKLCGPAYANEVVVYKGDIYGIPKTKKW
RSFFEEGVPTGIRYIDGFAYYAARKVEEAAMREQEEVKVKARIVENLSDI
NLYIHENVRRYILWKKGKIDVRGPLFVTVKAEIE
Ligand information
>2du6 Chain D (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccaggguggcagaggggcuuugcggcggacucuagauccgcuuuacccc
gguucgaauccgggcccuggc
.<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB2du6 Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		N420 T423 G443 W450 D520 R522 G523 P524
Binding residue
(residue number reindexed from 1)		N420 T423 G443 W450 D520 R522 G523 P524
Enzymatic activity
Enzyme Commision number 6.1.1.27: O-phosphoserine--tRNA ligase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0042802 identical protein binding
GO:0043816 phosphoserine-tRNA(Cys) ligase activity
Biological Process
GO:0006412 translation
GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2du6, PDBe:2du6, PDBj:2du6
PDBsum2du6
PubMed17351629
UniProtO30126|SEPS_ARCFU O-phosphoserine--tRNA(Cys) ligase (Gene Name=sepS)

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