Structure of PDB 2dpk Chain A Binding Site BS01

Receptor Information
>2dpk Chain A (length=124) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGIPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTA
NAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVKVS
SESALACLGSPSTATVTIFDDDHA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2dpk Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2dpk The crystal structure of the primary Ca2+ sensor of the na+/ca2+ exchanger reveals a novel Ca2+ binding motif.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D421 E451 E454
Binding residue
(residue number reindexed from 1)		D55 E85 E88
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007154 cell communication
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:2dpk, PDBe:2dpk, PDBj:2dpk
PDBsum2dpk
PubMed16774926
UniProtP23685|NAC1_CANLF Sodium/calcium exchanger 1 (Gene Name=SLC8A1)

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