Structure of PDB 2d4c Chain A Binding Site BS01

Receptor Information
>2d4c Chain A (length=224) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
NPASRAKLYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEV
KDSLDIEVKQNFIDPLQNLHDKDLREIQSALQHHLKKLEGRRLDFDYKKK
RQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQL
EYHKQAVQILQQVTVRLEERIRQA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2d4c Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2d4c Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D195 E199
Binding residue
(residue number reindexed from 1)		D168 E172
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.1.-
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:2d4c, PDBe:2d4c, PDBj:2d4c
PDBsum2d4c
PubMed16763557
UniProtQ99962|SH3G2_HUMAN Endophilin-A1 (Gene Name=SH3GL2)

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