Structure of PDB 2d3i Chain A Binding Site BS01

Receptor Information
>2d3i Chain A (length=670) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVIRWCTISSPEEKKCNNLRDLTQQERISLTCVQKATYLDCIKAIANNEA
DAISLDGGQVFEAGLAPYKLKPIAAEVYEHTEGSTTSYYAVAVVKKGTEF
TVNDLQGKTSCHTGLGRSAGWNIPIGTLIHRGAIEWEGIESGSVEQAVAK
FFSASCVPGATIEQKLCRQCKGDPKTKCARNAPYSGYSGAFHCLKDGKGD
VAFVKHTTVNENAPDQKDEYELLCLDGSRQPVDNYKTCNWARVAAHAVVA
RDDNKVEDIWSFLSKAQSDFGVDTKSDFHLFGPPGKKDPVLKDLLFKDSA
IMLKRVPSLMDSQLYLGFEYYSAIQSMRKDQENRIQWCAVGKDEKSKCDR
WSVVSNGDVECTVVDETKDCIIKIMKGEADAVALDGGLVYTAGVCGLVPV
MAERYDDESQCPASYFAVAVARKDSNVNWNNLKGKKSCHTAVGRTAGWVI
PMGLIHNRTGTCNFDEYFSEGCAPGSPPNSRLCQLCQGSGGIPPEKCVAS
SHEKYFGYTGALRCLVEKGDVAFIQHSTVEENTGGKNKADWAKNLQMDDF
ELLCTDGRRANVMDYRECNLAEVPTHAVVVRPEKANKIRDLLERQEKRFG
VNGSEKSKFMMFESQNKDLLFKDLTKCLFKVREGTTYKEFLGDKFYTVIS
SLKTCNPSDILQMCSFLEGK
Ligand information
Ligand IDBCT
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)(O)[O-]
CACTVS 3.341OC([O-])=O
ACDLabs 10.04[O-]C(=O)O
FormulaC H O3
NameBICARBONATE ION
ChEMBL
DrugBank
ZINC
PDB chain2d3i Chain A Residue 688 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2d3i Structure of aluminium-bound ovotransferrin at 2.15 Angstroms resolution.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		D60 Y92 T117 R121 A123 Y191 H250
Binding residue
(residue number reindexed from 1)		D56 Y88 T113 R117 A119 Y187 H246
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0008199 ferric iron binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006880 intracellular sequestering of iron ion
GO:0006881 extracellular sequestering of iron ion
GO:0006953 acute-phase response
GO:0009410 response to xenobiotic stimulus
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0032496 response to lipopolysaccharide
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0055037 recycling endosome
GO:1990377 organomineral extracellular matrix

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2d3i, PDBe:2d3i, PDBj:2d3i
PDBsum2d3i
PubMed16301797
UniProtP02789|TRFE_CHICK Ovotransferrin

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