Structure of PDB 2d10 Chain A Binding Site BS01

Receptor Information
>2d10 Chain A (length=295) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDS
KGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLF
FLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRL
LPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYG
VNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFND
KKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKP
Ligand information
>2d10 Chain E (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SSKRAPQMDWSKKNELFSNL
Receptor-Ligand Complex Structure
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PDB2d10 Structural basis for NHERF recognition by ERM proteins
Resolution2.5 Å
Binding residue
(original residue number in PDB)
N210 K211 K212 P236 I238 G239 F240 E244 I257 P259 P265 F267
Binding residue
(residue number reindexed from 1)
N208 K209 K210 P234 I236 G237 F238 E242 I255 P257 P263 F265
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0008092 cytoskeletal protein binding
Cellular Component
GO:0005856 cytoskeleton

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Molecular Function

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Cellular Component
External links
PDB RCSB:2d10, PDBe:2d10, PDBj:2d10
PDBsum2d10
PubMed16615918
UniProtP26043|RADI_MOUSE Radixin (Gene Name=Rdx)

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