Structure of PDB 2ctc Chain A Binding Site BS01

Receptor Information

>2ctc Chain A (length=307) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ARSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVL
KFSTGGSNRPAIWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAIL
DSMDIFLEIVTNPDGFAFTHSQNRLWRKTRSVTSSSLCVGVDANRNWDAG
FGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHGNFKAFLSIHSYSQ
LLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYGSIITTIYQA
SGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTI
MEHTLNN

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

2ctc Chain A Residue 308 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2ctc High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Resolution	1.4 Å
Binding residue (original residue number in PDB)	H69 E72 H196
Binding residue (residue number reindexed from 1)	H69 E72 H196
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H69 E72 R127 H196 E270
Catalytic site (residue number reindexed from 1)	H69 E72 R127 H196 E270
Enzyme Commision number	3.4.17.1: carboxypeptidase A.

Gene Ontology

	Molecular Function
GO:0004181	metallocarboxypeptidase activity
GO:0008270	zinc ion binding

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:2ctc, PDBe:2ctc, PDBj:2ctc
PDBsum	2ctc
PubMed	15299490
UniProt	P00730\|CBPA1_BOVIN Carboxypeptidase A1 (Gene Name=CPA1)

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