Structure of PDB 2cs8 Chain A Binding Site BS01

Receptor Information
>2cs8 Chain A (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSSGSSGPELKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKENPLNG
ASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQVIKKGK
VSSGPSSG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2cs8 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cs8 Solution structure of tandem repeat of the fifth and sixth zinc-finger C2HC domains from human ST18
ResolutionN/A
Binding residue
(original residue number in PDB)		C12 C17 H30 C36
Binding residue
(residue number reindexed from 1)		C12 C17 H30 C36
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cs8, PDBe:2cs8, PDBj:2cs8
PDBsum2cs8
PubMed
UniProtO60284|ST18_HUMAN Suppression of tumorigenicity 18 protein (Gene Name=ST18)

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