Structure of PDB 2cm6 Chain A Binding Site BS01

Receptor Information
>2cm6 Chain A (length=149) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MALYEEEQVERIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYS
DPFVKLWLKPKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISV
WDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2cm6 Chain A Residue 1679 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cm6 The C2A-C2B Linker Defines the High Affinity Ca2+ Binding Mode of Rabphilin-3A.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		D571 D577 D631 Y632 D633
Binding residue
(residue number reindexed from 1)		D45 D51 D102 Y103 D104
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:2cm6, PDBe:2cm6, PDBj:2cm6
PDBsum2cm6
PubMed17166855
UniProtP47709|RP3A_RAT Rabphilin-3A (Gene Name=Rph3a)

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