Structure of PDB 2cm5 Chain A Binding Site BS01

Receptor Information
>2cm5 Chain A (length=144) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MALYEEEIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFV
KLWLKPDKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD
IGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQN
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2cm5 Chain A Residue 1678 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cm5 The C2A-C2B Linker Defines the High Affinity Ca2+ Binding Mode of Rabphilin-3A.
Resolution1.28 Å
Binding residue
(original residue number in PDB)		E529 M570 D571 D631 D633 D639
Binding residue
(residue number reindexed from 1)		E6 M40 D41 D98 D100 D106
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:2cm5, PDBe:2cm5, PDBj:2cm5
PDBsum2cm5
PubMed17166855
UniProtP47709|RP3A_RAT Rabphilin-3A (Gene Name=Rph3a)

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