Structure of PDB 2cf4 Chain A Binding Site BS01

Receptor Information
>2cf4 Chain A (length=330) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMIEKLKKFTQIPGISGYEERIREEIIREIKDFADYKVDAIGNLIVELGE
GEERILFMAHMDEIGLLITGITDEGKLRFRKVGGIDDRLLYGRHVNVVTE
KGILDGVIGATPPHLSLERDKSVIPWYDLVIDIGAESKEEALELVKPLDF
AVFKKHFSVLNGKYVSTRGLDDRFGVVALIEAIKDLVDHELEGKVIFAFT
VQEEVGLKGAKFLANHYYPQYAFAIDSFACCSPLTGDVKLGKGPVIRAVD
NSAIYSRDLARKVWSIAEKNGIEIQIGVTGGGTDASAFQDRSKTLALSVP
IKYLHSEVETLHLNDLEKLVKLIEALAFEL
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain2cf4 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cf4 An Archaeal Peptidase Assembles Into Two Different Quaternary Structures: A Tetrahedron and a Giant Octahedron.
Resolution3.08 Å
Binding residue
(original residue number in PDB)		D172 E205 H306
Binding residue
(residue number reindexed from 1)		D171 E204 H305
Annotation score3
Enzymatic activity
Enzyme Commision number 3.4.11.-
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2cf4, PDBe:2cf4, PDBj:2cf4
PDBsum2cf4
PubMed16973604
UniProtO58255

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