Structure of PDB 2cax Chain A Binding Site BS01

Receptor Information

>2cax Chain A (length=53) Species: 1314 (Streptococcus pyogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MAKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMDQALEEYIRKYLP
DKL

Ligand information

>2cax Chain Y (length=18) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cttgtgacttgtgattcg

Receptor-Ligand Complex Structure

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PDB	2cax Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	H37 K41 N50 V51 K52
Binding residue (residue number reindexed from 1)	H19 K23 N32 V33 K34
Binding affinity	PDBbind-CN: Kd=40nM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Biological Process

External links

PDB	RCSB:2cax, PDBe:2cax, PDBj:2cax
PDBsum	2cax
PubMed	16528102
UniProt	Q57468

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