Structure of PDB 2c6b Chain A Binding Site BS01

Receptor Information
>2c6b Chain A (length=46) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2c6b Chain A Residue 336 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2c6b Solution Structure of the C4 Zinc Finger Domain of Hdm2.
ResolutionN/A
Binding residue
(original residue number in PDB)		C305 C308 C319 C322
Binding residue
(residue number reindexed from 1)		C16 C19 C30 C33
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:2c6b, PDBe:2c6b, PDBj:2c6b
PDBsum2c6b
PubMed16385008
UniProtQ00987|MDM2_HUMAN E3 ubiquitin-protein ligase Mdm2 (Gene Name=MDM2)

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