Structure of PDB 2c60 Chain A Binding Site BS01

Receptor Information
>2c60 Chain A (length=85) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTENLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMN
NELSILLKNQDDLDKAIDILDRSSSMKSLRILLLS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2c60 Chain A Residue 1123 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2c60 Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase Kinase 3 Isoform 2 Fox Domain at 1.25 A Resolution
Resolution1.25 Å
Binding residue
(original residue number in PDB)		L107 S110 M113
Binding residue
(residue number reindexed from 1)		L70 S73 M76
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.25: mitogen-activated protein kinase kinase kinase.
External links
PDB RCSB:2c60, PDBe:2c60, PDBj:2c60
PDBsum2c60
PubMed
UniProtQ99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 (Gene Name=MAP3K3)

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