Structure of PDB 2c5d Chain A Binding Site BS01

Receptor Information
>2c5d Chain A (length=380) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DILPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPTRLVAEFDFRTF
DPEGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHGM
WQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPF
HEKDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGS
FYPGSGFAFYSLDYMTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVA
LVDKQLVVLAVEHTALALMEIKVCDGQEHVVTVSLRDGEATLEVDGTRGQ
SEVSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTL
EVNRRLLDLDEAAYKHSDITAHSCPPVEPA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2c5d Chain A Residue 1677 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2c5d Structural Basis for Gas6-Axl Signalling.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		D329 E331 R440 D656
Binding residue
(residue number reindexed from 1)		D51 E53 R162 D360
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2c5d, PDBe:2c5d, PDBj:2c5d
PDBsum2c5d
PubMed16362042
UniProtQ14393|GAS6_HUMAN Growth arrest-specific protein 6 (Gene Name=GAS6)

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