Structure of PDB 2c3a Chain A Binding Site BS01

Receptor Information
>2c3a Chain A (length=252) Species: 10298 (Human alphaherpesvirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLDQLTDPPGVRRCYHIQAGLPDPFQPPSLPITVYYAVLERACRSVLLNA
PSEAPQIVRGASEDVRKQPYNLTIAWFRMGGNCAIPITVMEYTECSYNKS
LGACPIRTQPRWNYYDSFSAVSDNLGFLMHAPAFETAGTYLRLVKINDWT
EITQFILEHRAKGSCKYALPLRIPPSACLSPQAYQQGVTVDSIGMLPRFI
PENQRTVAVYSLKIAGWHGPKAPYTSTLLPPVAPQIPPNWHIPSIQDCAT
PY
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2c3a Chain A Residue 1310 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2c3a Structure of Unliganded Hsv Gd Reveals a Mechanism for Receptor-Mediated Activation of Virus Entry.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D147 E226
Binding residue
(residue number reindexed from 1)		D123 E202
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:2c3a, PDBe:2c3a, PDBj:2c3a
PDBsum2c3a
PubMed16292345
UniProtP57083|GD_HHV1P Envelope glycoprotein D (Gene Name=gD)

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