Structure of PDB 2bd7 Chain A Binding Site BS01
Receptor Information
>2bd7 Chain A (length=240) Species:
9823
(Sus scrofa) [
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VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRE
LTFRVVVGEHNLNQNNGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLA
QSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYL
PTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQY
AVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN
Ligand information
>2bd7 Chain P (length=1) Species:
9606
(Homo sapiens) [
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I
Receptor-Ligand Complex Structure
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PDB
2bd7
Structural analyses on intermediates in serine protease catalysis
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
H57 C191 Q192 G193 D194 S195 T213 V216
Binding residue
(residue number reindexed from 1)
H45 C184 Q185 G186 D187 S188 T206 V209
Enzymatic activity
Enzyme Commision number
3.4.21.36
: pancreatic elastase.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
GO:0005515
protein binding
GO:0008236
serine-type peptidase activity
GO:0046872
metal ion binding
Biological Process
GO:0006508
proteolysis
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
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Molecular Function
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Cellular Component
External links
PDB
RCSB:2bd7
,
PDBe:2bd7
,
PDBj:2bd7
PDBsum
2bd7
PubMed
16754679
UniProt
P00772
|CELA1_PIG Chymotrypsin-like elastase family member 1 (Gene Name=CELA1)
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