Structure of PDB 2bbr Chain A Binding Site BS01

Receptor Information
>2bbr Chain A (length=189) Species: 10280 (Molluscum contagiosum virus subtype 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDSKEVPSLPFLRHLLEELDSHEDSLLLFLCHDAAPGCTTVTQALCSLSQ
QRKLTLAALVEMLYVLQRMDLLKSRFGLSKEGAEQLLGTSFLTRYRKLMV
CVGEELDSSELRALRLFACNLNPSLSTALSESSRFVELVLALENVGLVSP
SSVSVLADMLRTLRRLDLCQQLVEYEQQEQARYRYCLHH
Ligand information
Ligand IDAZI
InChIInChI=1S/N3/c1-3-2/q-1
InChIKeyIVRMZWNICZWHMI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[N-]=[N+]=[N-]
FormulaN3
NameAZIDE ION
ChEMBLCHEMBL79455
DrugBank
ZINC
PDB chain2bbr Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2bbr Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		L88 R95 K98
Binding residue
(residue number reindexed from 1)		L87 R94 K97
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2bbr, PDBe:2bbr, PDBj:2bbr
PDBsum2bbr
PubMed16364918
UniProtQ98325|CFLA_MCV1 Viral CASP8 and FADD-like apoptosis regulator (Gene Name=MC159L)

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