Structure of PDB 2b2w Chain A Binding Site BS01
Receptor Information
>2b2w Chain A (length=177) Species:
9606
(Homo sapiens) [
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EEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQY
LIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASP
EDVEYYNCQQELTDDLHKQYQIVGRIIAHSNQKSAAGYPDYYCKWQGLPY
SECSWEDGALISKKFQACIDEYFSRKK
Ligand information
>2b2w Chain D (length=5) Species:
9606
(Homo sapiens) [
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ARTKQ
Receptor-Ligand Complex Structure
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PDB
2b2w
Double chromodomains cooperate to recognize the methylated histone H3 tail.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
E14 Y37 W64 W67 D150 D167
Binding residue
(residue number reindexed from 1)
E4 Y27 W54 W57 D140 D157
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
External links
PDB
RCSB:2b2w
,
PDBe:2b2w
,
PDBj:2b2w
PDBsum
2b2w
PubMed
16372014
UniProt
O14646
|CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (Gene Name=CHD1)
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