Structure of PDB 2b2u Chain A Binding Site BS01

Receptor Information
>2b2u Chain A (length=173) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKEPGEIQYLIKW
KGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVE
YYNCQQELTDDLHKQYQIVGRIIAHSNQKSAAGYPDYYCKWQGLPYSECS
WEDGALISKKFQACIDEYFSRKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2b2u Double chromodomains cooperate to recognize the methylated histone H3 tail.
Resolution2.95 Å
Binding residue
(original residue number in PDB)
E14 Y37 G66 W67 D150
Binding residue
(residue number reindexed from 1)
E2 Y25 G52 W53 D136
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
External links
PDB RCSB:2b2u, PDBe:2b2u, PDBj:2b2u
PDBsum2b2u
PubMed16372014
UniProtO14646|CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (Gene Name=CHD1)

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