Structure of PDB 2b23 Chain A Binding Site BS01
Receptor Information
>2b23 Chain A (length=229) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTFDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>2b23 Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2b23
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I50 K54 L64 V68 E72 D219 L220 E223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2b23
,
PDBe:2b23
,
PDBj:2b23
PDBsum
2b23
PubMed
18344977
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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